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Serotoninergic receptor ligands improve Tamoxifen effectiveness on breast cancer cells

BACKGROUND: Serotonin (or 5-Hydroxytryptamine, 5-HT) signals in mammary gland becomes dysregulated in cancer, also contributing to proliferation, metastasis, and angiogenesis. Thus, the discovery of novel compounds targeting serotonin signaling may contribute to tailor new therapeutic strategies usa...

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Detalles Bibliográficos
Autores principales: Ambrosio, Maria Rosaria, Magli, Elisa, Caliendo, Giuseppe, Sparaco, Rosa, Massarelli, Paola, D’Esposito, Vittoria, Migliaccio, Teresa, Mosca, Giusy, Fiorino, Ferdinando, Formisano, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8845285/
https://www.ncbi.nlm.nih.gov/pubmed/35168555
http://dx.doi.org/10.1186/s12885-021-09147-y