Cargando…

CD34(+)THY1(+) synovial fibroblast subset in arthritic joints has high osteoblastic and chondrogenic potentials in vitro

OBJECTIVE: Synovial fibroblasts (SFs) in rheumatoid arthritis (RA) and osteoarthritis (OA) play biphasic roles in joint destruction and regeneration of bone/cartilage as mesenchymal stem cells (MSCs). Although MSCs contribute to joint homeostasis, such function is impaired in arthritic joints. We ha...

Descripción completa

Detalles Bibliográficos
Autores principales: Noda, Seiji, Hosoya, Tadashi, Komiya, Yoji, Tagawa, Yasuhiro, Endo, Kentaro, Komori, Keiichiro, Koga, Hideyuki, Takahara, Yasuhiro, Sugimoto, Kazutaka, Sekiya, Ichiro, Saito, Tetsuya, Mizoguchi, Fumitaka, Yasuda, Shinsuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8845288/
https://www.ncbi.nlm.nih.gov/pubmed/35168627
http://dx.doi.org/10.1186/s13075-022-02736-7