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CD34(+)THY1(+) synovial fibroblast subset in arthritic joints has high osteoblastic and chondrogenic potentials in vitro
OBJECTIVE: Synovial fibroblasts (SFs) in rheumatoid arthritis (RA) and osteoarthritis (OA) play biphasic roles in joint destruction and regeneration of bone/cartilage as mesenchymal stem cells (MSCs). Although MSCs contribute to joint homeostasis, such function is impaired in arthritic joints. We ha...
Autores principales: | Noda, Seiji, Hosoya, Tadashi, Komiya, Yoji, Tagawa, Yasuhiro, Endo, Kentaro, Komori, Keiichiro, Koga, Hideyuki, Takahara, Yasuhiro, Sugimoto, Kazutaka, Sekiya, Ichiro, Saito, Tetsuya, Mizoguchi, Fumitaka, Yasuda, Shinsuke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8845288/ https://www.ncbi.nlm.nih.gov/pubmed/35168627 http://dx.doi.org/10.1186/s13075-022-02736-7 |
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