Computational identification of clonal cells in single-cell CRISPR screens

BACKGROUND: Single-cell CRISPR screens are powerful tools to understand genome function by linking genetic perturbations to transcriptome-wide phenotypes. However, since few cells can be affordably sequenced in these screens, biased sampling of cells could affect data interpretation. One potential s...

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Detalles Bibliográficos
Autores principales: Wang, Yihan, Xie, Shiqi, Armendariz, Daniel, Hon, Gary C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8845350/
https://www.ncbi.nlm.nih.gov/pubmed/35168568
http://dx.doi.org/10.1186/s12864-022-08359-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8845350/
https://www.ncbi.nlm.nih.gov/pubmed/35168568
http://dx.doi.org/10.1186/s12864-022-08359-1

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