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Computational identification of clonal cells in single-cell CRISPR screens

BACKGROUND: Single-cell CRISPR screens are powerful tools to understand genome function by linking genetic perturbations to transcriptome-wide phenotypes. However, since few cells can be affordably sequenced in these screens, biased sampling of cells could affect data interpretation. One potential s...

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Detalles Bibliográficos
Autores principales:	Wang, Yihan, Xie, Shiqi, Armendariz, Daniel, Hon, Gary C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8845350/ https://www.ncbi.nlm.nih.gov/pubmed/35168568 http://dx.doi.org/10.1186/s12864-022-08359-1

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