Cargando…

Prediction of liquid–liquid phase separating proteins using machine learning

BACKGROUND: The liquid–liquid phase separation (LLPS) of biomolecules in cell underpins the formation of membraneless organelles, which are the condensates of protein, nucleic acid, or both, and play critical roles in cellular function. Dysregulation of LLPS is implicated in a number of diseases. Al...

Descripción completa

Detalles Bibliográficos
Autores principales: Chu, Xiaoquan, Sun, Tanlin, Li, Qian, Xu, Youjun, Zhang, Zhuqing, Lai, Luhua, Pei, Jianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8845408/
https://www.ncbi.nlm.nih.gov/pubmed/35168563
http://dx.doi.org/10.1186/s12859-022-04599-w