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Prediction of liquid–liquid phase separating proteins using machine learning
BACKGROUND: The liquid–liquid phase separation (LLPS) of biomolecules in cell underpins the formation of membraneless organelles, which are the condensates of protein, nucleic acid, or both, and play critical roles in cellular function. Dysregulation of LLPS is implicated in a number of diseases. Al...
Autores principales: | Chu, Xiaoquan, Sun, Tanlin, Li, Qian, Xu, Youjun, Zhang, Zhuqing, Lai, Luhua, Pei, Jianfeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8845408/ https://www.ncbi.nlm.nih.gov/pubmed/35168563 http://dx.doi.org/10.1186/s12859-022-04599-w |
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