Intron-Retention Neoantigen Load Predicts Favorable Prognosis in Pancreatic Cancer

High tumor mutation burden (TMB) in many cancer types is associated with the production of tumor-specific neoantigens, a favorable outcome and response to immune checkpoint blockade (ICB) therapy. Besides mutation-derived neoantigens, aberrant intron retention also produces tumor neopeptides that co...

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Detalles Bibliográficos
Autores principales: Dong, Chuanpeng, Reiter, Jill L., Dong, Edward, Wang, Yue, Lee, Kelvin P., Lu, Xiongbin, Liu, Yunlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2022
Materias:
ORIGINAL REPORTS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846286/
https://www.ncbi.nlm.nih.gov/pubmed/35148169
http://dx.doi.org/10.1200/CCI.21.00124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846286/
https://www.ncbi.nlm.nih.gov/pubmed/35148169
http://dx.doi.org/10.1200/CCI.21.00124

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