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EPO activates PI3K-IKKα-CDK1 signaling pathway to promote the proliferation of Glial Cells under hypoxia environment

Erythropoietin (EPO), supports the function and survival of neurons through astrocytes and has a protective role in neonatal asphyxia brain injury; yet, its mechanism of action remains unclear. As a neuroprotective factor, EPO is also used in the treatment of various diseases, such as neurodegenerat...

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Detalles Bibliográficos
Autores principales: Hu, Gejile, Wang, Ting, Ma, Chunjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846297/
https://www.ncbi.nlm.nih.gov/pubmed/35167649
http://dx.doi.org/10.1590/1678-4685-GMB-2021-0249