Population Pharmacokinetic and Concentration-QTc Analysis of Delamanid in Pediatric Participants with Multidrug-Resistant Tuberculosis

A population pharmacokinetic analysis of delamanid and its major metabolite DM-6705 was conducted to characterize the pharmacokinetics of delamanid and DM-6705 in pediatric participants with multidrug-resistant tuberculosis (MDR-TB). Data from participants between the ages of 0.67 and 17 years, enro...

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Detalles Bibliográficos
Autores principales: Sasaki, Tomohiro, Svensson, Elin M., Wang, Xiaofeng, Wang, Yanlin, Hafkin, Jeffrey, Karlsson, Mats O., Mallikaarjun, Suresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Clinical Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846319/
https://www.ncbi.nlm.nih.gov/pubmed/34843388
http://dx.doi.org/10.1128/AAC.01608-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846319/
https://www.ncbi.nlm.nih.gov/pubmed/34843388
http://dx.doi.org/10.1128/AAC.01608-21

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