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A Photoactivable Natural Product with Broad Antiviral Activity against Enveloped Viruses, Including Highly Pathogenic Coronaviruses

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak has highlighted the need for broad-spectrum antivirals against coronaviruses (CoVs). Here, pheophorbide a (Pba) was identified as a highly active antiviral molecule against human CoV-229E after bioguided fractionation of plant...

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Detalles Bibliográficos
Autores principales: Meunier, Thomas, Desmarets, Lowiese, Bordage, Simon, Bamba, Moussa, Hervouet, Kévin, Rouillé, Yves, François, Nathan, Decossas, Marion, Sencio, Valentin, Trottein, François, Tra Bi, Fézan Honora, Lambert, Olivier, Dubuisson, Jean, Belouzard, Sandrine, Sahpaz, Sevser, Séron, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846325/
https://www.ncbi.nlm.nih.gov/pubmed/34807755
http://dx.doi.org/10.1128/AAC.01581-21