Liver-specific microRNA-185 knockout promotes cholesterol dysregulation in mice

BACKGROUND: The liver plays a key role in regulating whole body cholesterol homeostasis. Hepatic cholesterol accumulation causes liver injury in fatty liver disease and hypercholesterolemia increases the risk of cardiovascular disease. MicroRNAs (miRNAs, miRs) have been shown to regulate various pat...

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Detalles Bibliográficos
Autores principales: Chen, Cheng, Matye, David, Wang, Yifeng, Li, Tiangang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846416/
https://www.ncbi.nlm.nih.gov/pubmed/35173984
http://dx.doi.org/10.1016/j.livres.2020.09.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846416/
https://www.ncbi.nlm.nih.gov/pubmed/35173984
http://dx.doi.org/10.1016/j.livres.2020.09.001

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