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Early Bactericidal Activity of Delpazolid (LCB01-0371) in Patients with Pulmonary Tuberculosis

Delpazolid, an oxazolidinone, has been studied in non-clinical studies of efficacy and toxicity and Phase 1 clinical studies. Delpazolid has in vitro activity against Gram-positive bacteria, including Mycobacterium tuberculosis. This study evaluated the bactericidal activity, safety, and pharmacokin...

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Detalles Bibliográficos
Autores principales: Kim, Ju Sang, Kim, Yong-hyun, Lee, Sang Haak, Kim, Yee Hyung, Kim, Jin-woo, Kang, Ji Young, Kim, Sung Kyoung, Kim, Seung Joon, Kang, Yun-Seong, Kim, Tae-hyung, Mok, Jeongha, Byun, Min Kwang, Park, Hye Jung, Joh, Joon-sung, Park, Yong Bum, Lim, Hyeong-Seok, Choi, Hongjo, Lee, Seung Heon, Kim, Hyejin, Yang, Jeongseong, Kim, Hyunji, Shen, Xianlin, Alsultan, Abdullah, Cho, InSook, Geiter, Lawrence, Shim, Tae Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846473/
https://www.ncbi.nlm.nih.gov/pubmed/34871098
http://dx.doi.org/10.1128/aac.01684-21