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DNAJB1-PRKACA in HEK293T cells induces LINC00473 overexpression that depends on PKA signaling

Fibrolamellar carcinoma (FLC) is a primary liver cancer that most commonly arises in adolescents and young adults in a background of normal liver tissue and has a poor prognosis due to lack of effective chemotherapeutic agents. The DNAJB1-PRKACA gene fusion (DP) has been reported in the majority of...

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Detalles Bibliográficos
Autores principales: Kim, Stephanie S., Kycia, Ina, Karski, Michael, Ma, Rosanna K., Bordt, Evan A., Kwan, Julian, Karki, Anju, Winter, Elle, Aktas, Ranan G., Wu, Yuxuan, Emili, Andrew, Bauer, Daniel E., Sethupathy, Praveen, Vakili, Khashayar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846505/
https://www.ncbi.nlm.nih.gov/pubmed/35167623
http://dx.doi.org/10.1371/journal.pone.0263829