Itaconate and derivatives reduce interferon responses and inflammation in influenza A virus infection

Excessive inflammation is a major cause of morbidity and mortality in many viral infections including influenza. Therefore, there is a need for therapeutic interventions that dampen and redirect inflammatory responses and, ideally, exert antiviral effects. Itaconate is an immunomodulatory metabolite...

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Detalles Bibliográficos
Autores principales: Sohail, Aaqib, Iqbal, Azeem A., Sahini, Nishika, Chen, Fangfang, Tantawy, Mohamed, Waqas, Syed F.H., Winterhoff, Moritz, Ebensen, Thomas, Schultz, Kristin, Geffers, Robert, Schughart, Klaus, Preusse, Matthias, Shehata, Mahmoud, Bähre, Heike, Pils, Marina C., Guzman, Carlos A., Mostafa, Ahmed, Pleschka, Stephan, Falk, Christine, Michelucci, Alessandro, Pessler, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846506/
https://www.ncbi.nlm.nih.gov/pubmed/35025971
http://dx.doi.org/10.1371/journal.ppat.1010219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846506/
https://www.ncbi.nlm.nih.gov/pubmed/35025971
http://dx.doi.org/10.1371/journal.ppat.1010219

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