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Integrated functional and spatial profiling of tumour immune responses induced by immunotherapy: the iPROFILER platform

BACKGROUND: Cancer immunotherapy elicits functional activation and changes in immune cell distribution in cancer. Tumour heterogeneity is a reason for treatment failure but is difficult to capture in experimental settings. This proof-of-principle study describes the integrated functional and digital...

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Detalles Bibliográficos
Autores principales: Koelzer, V.H., Herzig, P., Zlobec, I., Heinzelmann, V., Lardinois, D., Walseng, E., Rader, C., Mertz, K.D., Zippelius, A., Thommen, D.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846576/
https://www.ncbi.nlm.nih.gov/pubmed/35174321
http://dx.doi.org/10.1016/j.iotech.2021.100034