Reversing chemorefraction in colorectal cancer cells by controlling mucin secretion

Fifteen percent of colorectal cancer (CRC) cells exhibit a mucin hypersecretory phenotype, which is suggested to provide resistance to immune surveillance and chemotherapy. We now formally show that CRC cells build a barrier to chemotherapeutics by increasing mucins’ secretion. We show that low leve...

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Detalles Bibliográficos
Autores principales: Cantero-Recasens, Gerard, Alonso-Marañón, Josune, Lobo-Jarne, Teresa, Garrido, Marta, Iglesias, Mar, Espinosa, Lluis, Malhotra, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846583/
https://www.ncbi.nlm.nih.gov/pubmed/35131032
http://dx.doi.org/10.7554/eLife.73926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846583/
https://www.ncbi.nlm.nih.gov/pubmed/35131032
http://dx.doi.org/10.7554/eLife.73926

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