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A stochastic mixed effects model to assess treatment effects and fluctuations in home‐measured peak expiratory flow and the association with exacerbation risk in asthma

Home‐based measures of lung function, inflammation, symptoms, and medication use are frequently collected in respiratory clinical trials. However, new statistical approaches are needed to make better use of the information contained in these data‐rich variables. In this work, we use data from two ph...

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Detalles Bibliográficos
Autores principales: Leander, Jacob, Jirstrand, Mats, Eriksson, Ulf G., Palmér, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846634/
https://www.ncbi.nlm.nih.gov/pubmed/34797036
http://dx.doi.org/10.1002/psp4.12748