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A stochastic mixed effects model to assess treatment effects and fluctuations in home‐measured peak expiratory flow and the association with exacerbation risk in asthma
Home‐based measures of lung function, inflammation, symptoms, and medication use are frequently collected in respiratory clinical trials. However, new statistical approaches are needed to make better use of the information contained in these data‐rich variables. In this work, we use data from two ph...
Autores principales: | Leander, Jacob, Jirstrand, Mats, Eriksson, Ulf G., Palmér, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846634/ https://www.ncbi.nlm.nih.gov/pubmed/34797036 http://dx.doi.org/10.1002/psp4.12748 |
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