An Erythropoietin-Independent Mechanism of Erythrocytic Precursor Proliferation Underlies Hypoxia Tolerance in Sea Nomads

The Bajau Sea Nomads were recently demonstrated to have evolved larger spleens as an adaptation to millennia of a marine foraging lifestyle. The large-spleen phenotype appears to derive from increases in thyroid hormone (TH) production as a result of reduced expression of phosphodiesterase 10A (PDE1...

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Detalles Bibliográficos
Autores principales: Ilardo, Melissa, dos Santos, Maria C. Ferreira, Grote Beverborg, Niels, Rajan, Malini, Said, M. Abdullah, Verweij, Niek, Van Der Harst, Pim, Van Der Meer, Peter, Leibold, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846933/
https://www.ncbi.nlm.nih.gov/pubmed/35177992
http://dx.doi.org/10.3389/fphys.2021.760851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846933/
https://www.ncbi.nlm.nih.gov/pubmed/35177992
http://dx.doi.org/10.3389/fphys.2021.760851

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