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Global pleiotropic effects in adaptively evolved Escherichia coli lacking CRP reveal molecular mechanisms that define the growth physiology

Evolution facilitates emergence of fitter phenotypes by efficient allocation of cellular resources in conjunction with beneficial mutations. However, system-wide pleiotropic effects that redress the perturbations to the apex node of the transcriptional regulatory networks remain unclear. Here, we el...

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Detalles Bibliográficos
Autores principales: Pal, Ankita, Iyer, Mahesh S., Srinivasan, Sumana, Narain Seshasayee, Aswin Sai, Venkatesh, K. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8846999/
https://www.ncbi.nlm.nih.gov/pubmed/35167766
http://dx.doi.org/10.1098/rsob.210206