Glycolytic inhibitor 2-deoxy-d-glucose attenuates SARS-CoV-2 multiplication in host cells and weakens the infective potential of progeny virions

AIMS: Virus-infected host cells switch their metabolism to a more glycolytic phenotype, required for new virion synthesis and packaging. Therefore, we investigated the effect and mechanistic action of glycolytic inhibitor 2-Deoxy-d-glucose (2-DG) on virus multiplication in host cells following SARS-...

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Detalles Bibliográficos
Autores principales: Bhatt, Anant Narayan, Kumar, Abhishek, Rai, Yogesh, Kumari, Neeraj, Vedagiri, Dhiviya, Harshan, Krishnan H., Chinnadurai, Vijayakumar, Chandna, Sudhir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847085/
https://www.ncbi.nlm.nih.gov/pubmed/35181310
http://dx.doi.org/10.1016/j.lfs.2022.120411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847085/
https://www.ncbi.nlm.nih.gov/pubmed/35181310
http://dx.doi.org/10.1016/j.lfs.2022.120411

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