Cargando…

Metformin induces insulin secretion by preserving pancreatic aquaporin 7 expression in type 2 diabetes mellitus

In the presence of metformin, the c‐Jun‐NH2‐terminal kinase and p38 pathways in β‐cells are inhibited, resulting in preserved aquaporin 7 expression and improved glycerol influx, thus maintaining insulin secretion.[Image: see text]

Detalles Bibliográficos
Autores principales: Kimura, Tomohiko, Kaneto, Hideaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847123/
https://www.ncbi.nlm.nih.gov/pubmed/34779127
http://dx.doi.org/10.1111/jdi.13709