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The Influence of AA29504 on GABA(A) Receptor Ligand Binding Properties and Its Implications on Subtype Selectivity

The unique pharmacological properties of δ-containing γ-aminobutyric acid type A receptors (δ-GABA(A)Rs) make them an attractive target for selective and persistent modulation of neuronal excitability. However, the availability of selective modulators targeting δ-GABA(A)Rs remains limited. AA29504 (...

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Detalles Bibliográficos
Autores principales: Sikstus, Sylvia, Benkherouf, Ali Y., Soini, Sanna L., Uusi-Oukari, Mikko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847198/
https://www.ncbi.nlm.nih.gov/pubmed/34727270
http://dx.doi.org/10.1007/s11064-021-03475-y