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Clonally Expanded Virus-Specific CD8 T Cells Acquire Diverse Transcriptional Phenotypes During Acute, Chronic, and Latent Infections

CD8+ T cells play a crucial role in the control and resolution of viral infections and can adopt a wide range of phenotypes and effector functions depending on the inflammatory context and the duration and extent of antigen exposure. Similarly, viral infections can exert diverse selective pressures...

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Detalles Bibliográficos
Autores principales: Kuhn, Raphael, Sandu, Ioana, Agrafiotis, Andreas, Hong, Kai-Lin, Shlesinger, Danielle, Neimeier, Daniel, Merkler, Doron, Oxenius, Annette, Reddy, Sai T., Yermanos, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847396/
https://www.ncbi.nlm.nih.gov/pubmed/35185882
http://dx.doi.org/10.3389/fimmu.2022.782441