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Clonally Expanded Virus-Specific CD8 T Cells Acquire Diverse Transcriptional Phenotypes During Acute, Chronic, and Latent Infections
CD8+ T cells play a crucial role in the control and resolution of viral infections and can adopt a wide range of phenotypes and effector functions depending on the inflammatory context and the duration and extent of antigen exposure. Similarly, viral infections can exert diverse selective pressures...
Autores principales: | Kuhn, Raphael, Sandu, Ioana, Agrafiotis, Andreas, Hong, Kai-Lin, Shlesinger, Danielle, Neimeier, Daniel, Merkler, Doron, Oxenius, Annette, Reddy, Sai T., Yermanos, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847396/ https://www.ncbi.nlm.nih.gov/pubmed/35185882 http://dx.doi.org/10.3389/fimmu.2022.782441 |
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