TCR-Induced Tyrosine Phosphorylation at Tyr270 of SUMO Protease SENP1 by Lck Modulates SENP1 Enzyme Activity and Specificity

Small ubiquitin-like modifier (SUMO) modification plays an important regulatory role in T cell receptor (TCR) signaling transduction. SUMO-specific proteases (SENPs) have dual-enzyme activities; they can both process SUMO precursors as endopeptidases and participate in SUMO deconjugation as isopepti...

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Detalles Bibliográficos
Autores principales: Li, Yun-Yi, Cen, Haohua, Gong, Bei-Ni, Mai, Siqi, Wang, Qi-Long, Mou, Sisi, Li, Yingqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847397/
https://www.ncbi.nlm.nih.gov/pubmed/35186948
http://dx.doi.org/10.3389/fcell.2021.789348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847397/
https://www.ncbi.nlm.nih.gov/pubmed/35186948
http://dx.doi.org/10.3389/fcell.2021.789348

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