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Non-covalent SARS-CoV-2 M(pro) inhibitors developed from in silico screen hits

M(pro), the main protease of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is essential for the viral life cycle. Accordingly, several groups have performed in silico screens to identify M(pro) inhibitors that might be used to treat SARS-CoV-2 infections. We selected more than fi...

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Detalles Bibliográficos
Autores principales: Rossetti, Giacomo G., Ossorio, Marianna A., Rempel, Stephan, Kratzel, Annika, Dionellis, Vasilis S., Barriot, Samia, Tropia, Laurence, Gorgulla, Christoph, Arthanari, Haribabu, Thiel, Volker, Mohr, Peter, Gamboni, Remo, Halazonetis, Thanos D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847420/
https://www.ncbi.nlm.nih.gov/pubmed/35169179
http://dx.doi.org/10.1038/s41598-022-06306-4