Low pH Attenuates Apoptosis by Suppressing the Volume-Sensitive Outwardly Rectifying (VSOR) Chloride Current in Chondrocytes

In a variety of physiological and pathophysiological conditions, cells are exposed to acidic environments. Severe synovial fluid acidification also occurs in a progressive state of osteoarthritis (OA) affecting articular chondrocytes. In prior studies extracellular acidification has been shown to pr...

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Detalles Bibliográficos
Autores principales: Kittl, Michael, Winklmayr, Martina, Preishuber-Pflügl, Julia, Strobl, Victoria, Gaisberger, Martin, Ritter, Markus, Jakab, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847443/
https://www.ncbi.nlm.nih.gov/pubmed/35186954
http://dx.doi.org/10.3389/fcell.2021.804105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847443/
https://www.ncbi.nlm.nih.gov/pubmed/35186954
http://dx.doi.org/10.3389/fcell.2021.804105

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