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Low pH Attenuates Apoptosis by Suppressing the Volume-Sensitive Outwardly Rectifying (VSOR) Chloride Current in Chondrocytes
In a variety of physiological and pathophysiological conditions, cells are exposed to acidic environments. Severe synovial fluid acidification also occurs in a progressive state of osteoarthritis (OA) affecting articular chondrocytes. In prior studies extracellular acidification has been shown to pr...
Autores principales: | Kittl, Michael, Winklmayr, Martina, Preishuber-Pflügl, Julia, Strobl, Victoria, Gaisberger, Martin, Ritter, Markus, Jakab, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847443/ https://www.ncbi.nlm.nih.gov/pubmed/35186954 http://dx.doi.org/10.3389/fcell.2021.804105 |
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