Design of a mutation-integrated trimeric RBD with broad protection against SARS-CoV-2

The continuous emergence of SARS-CoV-2 variants highlights the need of developing vaccines with broad protection. Here, according to the immune-escape capability and evolutionary convergence, the representative SARS-CoV-2 strains carrying the hotspot mutations were selected. Then, guided by structur...

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Detalles Bibliográficos
Autores principales: Liang, Yu, Zhang, Jing, Yuan, Run Yu, Wang, Mei Yu, He, Peng, Su, Ji Guo, Han, Zi Bo, Jin, Yu Qin, Hou, Jun Wei, Zhang, Hao, Zhang, Xue Feng, Shao, Shuai, Hou, Ya Nan, Liu, Zhao Ming, Du, Li Fang, Shen, Fu Jie, Zhou, Wei Min, Xu, Ke, Gao, Ru Qin, Tang, Fang, Lei, Ze Hua, Liu, Shuo, Zhen, Wei, Wu, Jin Juan, Zheng, Xiang, Liu, Ning, Chen, Shi, Ma, Zhi Jing, Zheng, Fan, Ren, Si Yu, Hu, Zhong Yu, Huang, Wei Jin, Wu, Gui Zhen, Ke, Chang Wen, Li, Qi Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847466/
https://www.ncbi.nlm.nih.gov/pubmed/35169113
http://dx.doi.org/10.1038/s41421-022-00383-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847466/
https://www.ncbi.nlm.nih.gov/pubmed/35169113
http://dx.doi.org/10.1038/s41421-022-00383-5

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