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Organic anion transporter 1 is an HDAC4-regulated mediator of nociceptive hypersensitivity in mice

Persistent pain is sustained by maladaptive changes in gene transcription resulting in altered function of the relevant circuits; therapies are still unsatisfactory. The epigenetic mechanisms and affected genes linking nociceptive activity to transcriptional changes and pathological sensitivity are...

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Detalles Bibliográficos
Autores principales: Litke, Christian, Hagenston, Anna M., Kenkel, Ann-Kristin, Paldy, Eszter, Lu, Jianning, Kuner, Rohini, Mauceri, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847565/
https://www.ncbi.nlm.nih.gov/pubmed/35169129
http://dx.doi.org/10.1038/s41467-022-28357-x