Cargando…

Organic anion transporter 1 is an HDAC4-regulated mediator of nociceptive hypersensitivity in mice

Persistent pain is sustained by maladaptive changes in gene transcription resulting in altered function of the relevant circuits; therapies are still unsatisfactory. The epigenetic mechanisms and affected genes linking nociceptive activity to transcriptional changes and pathological sensitivity are...

Descripción completa

Detalles Bibliográficos
Autores principales:	Litke, Christian, Hagenston, Anna M., Kenkel, Ann-Kristin, Paldy, Eszter, Lu, Jianning, Kuner, Rohini, Mauceri, Daniela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847565/ https://www.ncbi.nlm.nih.gov/pubmed/35169129 http://dx.doi.org/10.1038/s41467-022-28357-x

Ejemplares similares

Epigenetic control of hypersensitivity in chronic inflammatory pain by the de novo DNA methyltransferase Dnmt3a2
por: Oliveira, Ana MM, et al.
Publicado: (2019)

The impact of Semaphorin 4C/Plexin-B2 signaling on fear memory via remodeling of neuronal and synaptic morphology
por: Simonetti, Manuela, et al.
Publicado: (2019)

Pain hypersensitivity mechanisms at a glance
por: Gangadharan, Vijayan, et al.
Publicado: (2013)

A role for Kalirin-7 in nociceptive sensitization via activity-dependent modulation of spinal synapses
por: Lu, Jianning, et al.
Publicado: (2015)

Semaphorin 4C Plexin-B2 signaling in peripheral sensory neurons is pronociceptive in a model of inflammatory pain
por: Paldy, Eszter, et al.
Publicado: (2017)

Prolonged Suppression of Neuropathic Hypersensitivity upon Neurostimulation of the Posterior Insula in Mice
por: Li, Han, et al.
Publicado: (2022)

Overview of organic anion transporters and organic anion transporter polypeptides and their roles in the liver
por: Li, Ting-Ting, et al.
Publicado: (2019)

Gamma oscillations in somatosensory cortex recruit prefrontal and descending serotonergic pathways in aversion and nociception
por: Tan, Linette Liqi, et al.
Publicado: (2019)

Experimental evidence for alleviating nociceptive hypersensitivity by single application of capsaicin
por: Ma, Xiao-Li, et al.
Publicado: (2015)

Nociception and hypersensitivity involve distinct neurons and molecular transducers in Drosophila
por: Gu, Pengyu, et al.
Publicado: (2022)

Regulation of organic anion transport in the liver.
por: Roelofsen, H., et al.
Publicado: (1997)

CGRP Administration Into the Cerebellum Evokes Light Aversion, Tactile Hypersensitivity, and Nociceptive Squint in Mice
por: Wang, Mengya, et al.
Publicado: (2022)

HCN2 Channels in the Ventral Hippocampal CA1 Regulate Nociceptive Hypersensitivity in Mice
por: Zheng, Yawen, et al.
Publicado: (2023)

Organic anion transporter 3- and organic anion transporting polypeptides 1B1- and 1B3-mediated transport of catalposide
por: Jeong, Hyeon-Uk, et al.
Publicado: (2015)

HDAC4 is required for inflammation-associated thermal hypersensitivity
por: Crow, Megan, et al.
Publicado: (2015)

Drosophila insulin receptor regulates diabetes-induced mechanical nociceptive hypersensitivity
por: Dabbara, Harika, et al.
Publicado: (2021)

Primary somatosensory cortex bidirectionally modulates sensory gain and nociceptive behavior in a layer-specific manner
por: Ziegler, Katharina, et al.
Publicado: (2023)

microRNAs in nociceptive circuits as predictors of future clinical applications
por: Kress, Michaela, et al.
Publicado: (2013)

HDAC inhibitors attenuate the development of hypersensitivity in models of neuropathic pain
por: Denk, Franziska, et al.
Publicado: (2013)

Drosophila model of anti-retroviral therapy induced peripheral neuropathy and nociceptive hypersensitivity
por: Bush, Keegan M., et al.
Publicado: (2021)

Loss of Pseudouridine Synthases in the RluA Family Causes Hypersensitive Nociception in Drosophila
por: Song, Wan, et al.
Publicado: (2020)

miR-34c-5p functions as pronociceptive microRNA in cancer pain by targeting Cav2.3 containing calcium channels
por: Gandla, Jagadeesh, et al.
Publicado: (2017)

Short-chain fatty acid, butyrate prevents morphine-and paclitaxel-induced nociceptive hypersensitivity
por: Jessup, Dawn, et al.
Publicado: (2023)

Lipopolysaccharide from Rhodobacter sphaeroides (TLR4 antagonist) attenuates hypersensitivity and modulates nociceptive factors
por: Jurga, Agnieszka M., et al.
Publicado: (2018)

Stimulatory effect on the transport mediated by organic anion transporting polypeptide 2B1
por: Ogura, Jiro, et al.
Publicado: (2020)

Tetrapodal Anion Transporters †
por: Gilchrist, Alexander M., et al.
Publicado: (2020)

Genome-wide identification and functional analyses of microRNA signatures associated with cancer pain
por: Bali, Kiran Kumar, et al.
Publicado: (2013)

Assessment of the Role of Renal Organic Anion Transporters in Drug-Induced Nephrotoxicity
por: Hagos, Yohannes, et al.
Publicado: (2010)

HvALMT1 from barley is involved in the transport of organic anions
por: Gruber, Benjamin D., et al.
Publicado: (2010)

Involvement of Organic Anion Transporters in the Pharmacokinetics and Drug Interaction of Rosmarinic Acid
por: Kang, Yun Ju, et al.
Publicado: (2021)

Renal Organic Anion Transporters 1 and 3 In Vitro: Gone but Not Forgotten
por: Caetano-Pinto, Pedro, et al.
Publicado: (2023)

Cortex: Unravelling the final frontier in pain
por: Kuner, Rohini
Publicado: (2017)

Tumor-Specific Expression of Organic Anion-Transporting Polypeptides: Transporters as Novel Targets for Cancer Therapy
por: Buxhofer-Ausch, Veronika, et al.
Publicado: (2013)

Immunohistochemical studies of organic anion transporters and urate transporter 1 expression in human salivary gland
por: Ikarashi, Ryuichi, et al.
Publicado: (2013)

Organic Anion Transporters (OAT) and Other SLC22 Transporters in Progression of Renal Cell Carcinoma
por: Whisenant, Thomas C., et al.
Publicado: (2022)

Minimizing the source of nociception and its concurrent effect on sensory hypersensitivity: An exploratory study in chronic whiplash patients
por: Schneider, Geoff M, et al.
Publicado: (2010)

Attenuation of myogenic orofacial nociception and mechanical hypersensitivity by viral mediated enkephalin overproduction in male and female rats
por: Kramer, Phillip R, et al.
Publicado: (2015)

Hypersensitivity of Prelimbic Cortex Neurons Contributes to Aggravated Nociceptive Responses in Rats With Experience of Chronic Inflammatory Pain
por: Fan, Xiao-Cen, et al.
Publicado: (2018)

Pain in experimental autoimmune encephalitis: a comparative study between different mouse models
por: Lu, Jianning, et al.
Publicado: (2012)

Effects of Increased Uric Acid Intake on the Abundance of Urate-anion exchanger and Organic Anion Transporter Proteins in the Rat Kidney
por: Kim, Sua, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_dl4r3vnb6d30lad3j2d4bbcbbc