IL-22 initiates an IL-18-dependent epithelial response circuit to enforce intestinal host defence

IL-18 is emerging as an IL-22-induced and epithelium-derived cytokine which contributes to host defence against intestinal infection and inflammation. In contrast to its known role in Goblet cells, regulation of barrier function at the molecular level by IL-18 is much less explored. Here we show tha...

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Detalles Bibliográficos
Autores principales: Chiang, Hung-Yu, Lu, Hsueh-Han, Sudhakar, Janaki N., Chen, Yu-Wen, Shih, Nien-Shin, Weng, Yi-Ting, Shui, Jr-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847568/
https://www.ncbi.nlm.nih.gov/pubmed/35169117
http://dx.doi.org/10.1038/s41467-022-28478-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847568/
https://www.ncbi.nlm.nih.gov/pubmed/35169117
http://dx.doi.org/10.1038/s41467-022-28478-3

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