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IL-22 initiates an IL-18-dependent epithelial response circuit to enforce intestinal host defence
IL-18 is emerging as an IL-22-induced and epithelium-derived cytokine which contributes to host defence against intestinal infection and inflammation. In contrast to its known role in Goblet cells, regulation of barrier function at the molecular level by IL-18 is much less explored. Here we show tha...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847568/ https://www.ncbi.nlm.nih.gov/pubmed/35169117 http://dx.doi.org/10.1038/s41467-022-28478-3 |