Liquid-Liquid Phase Separation of TDP-43 and FUS in Physiology and Pathology of Neurodegenerative Diseases

Liquid-liquid phase separation of RNA-binding proteins mediates the formation of numerous membraneless organelles with essential cellular function. However, aberrant phase transition of these proteins leads to the formation of insoluble protein aggregates, which are pathological hallmarks of neurode...

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Detalles Bibliográficos
Autores principales: Carey, Jenny L., Guo, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847598/
https://www.ncbi.nlm.nih.gov/pubmed/35187086
http://dx.doi.org/10.3389/fmolb.2022.826719

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847598/
https://www.ncbi.nlm.nih.gov/pubmed/35187086
http://dx.doi.org/10.3389/fmolb.2022.826719

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