PPARγ/SOD2 Protects Against Mitochondrial ROS-Dependent Apoptosis via Inhibiting ATG4D-Mediated Mitophagy to Promote Pancreatic Cancer Proliferation

Pancreatic ductal adenocarcinoma (PDAC) is an extremely aggressive disease with poor prognosis. Our previous study found that peroxisome proliferator activated receptor gamma (PPARγ) was capable of enhancing glycolysis in PDAC cells. However, whether PPARγ could promote PDAC progression remains uncl...

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Detalles Bibliográficos
Autores principales: Nie, Shuang, Shi, Zhao, Shi, Mengyue, Li, Hongzhen, Qian, Xuetian, Peng, Chunyan, Ding, Xiwei, Zhang, Shu, Lv, Ying, Wang, Lei, Kong, Bo, Zou, Xiaoping, Shen, Shanshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847684/
https://www.ncbi.nlm.nih.gov/pubmed/35186942
http://dx.doi.org/10.3389/fcell.2021.745554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847684/
https://www.ncbi.nlm.nih.gov/pubmed/35186942
http://dx.doi.org/10.3389/fcell.2021.745554

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