Regulation of Cholesterol Binding to the Receptor Patched1 by its interactions With the Ligand Sonic Hedgehog (Shh)

The Hedgehog (Hh) signaling pathway is essential in cell development and regeneration, which is activated by the ligand Sonic hedgehog (Shh). The binding of Shh to its receptor Patched1 (PTCH1) releases the inhibitory effect on the downstream protein Smoothened (SMO), a G-protein-coupled-receptor (G...

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Detalles Bibliográficos
Autores principales: Zhong, Changqing, Wang, Beibei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847689/
https://www.ncbi.nlm.nih.gov/pubmed/35187087
http://dx.doi.org/10.3389/fmolb.2022.831891

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847689/
https://www.ncbi.nlm.nih.gov/pubmed/35187087
http://dx.doi.org/10.3389/fmolb.2022.831891

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