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Cell-Free Expression to Probe Co-Translational Insertion of an Alpha Helical Membrane Protein

The majority of alpha helical membrane proteins fold co-translationally during their synthesis on the ribosome. In contrast, most mechanistic folding studies address refolding of full-length proteins from artificially induced denatured states that are far removed from the natural co-translational pr...

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Detalles Bibliográficos
Autores principales: Blackholly, Laura R., Harris, Nicola J., Findlay, Heather E., Booth, Paula J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847741/
https://www.ncbi.nlm.nih.gov/pubmed/35187078
http://dx.doi.org/10.3389/fmolb.2022.795212