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FKBP51 and FKBP52 regulate androgen receptor dimerization and proliferation in prostate cancer cells

The growth of prostate cancer is dependent on the androgen receptor (AR), which serves as a ligand‐specific transcription factor. Although two immunophilins, FKBP51 and FKBP52, are known to regulate AR activity, the precise mechanism remains unclear. We found that depletion of either FKBP51 or FKBP5...

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Detalles Bibliográficos
Autores principales: Maeda, Keisuke, Habara, Makoto, Kawaguchi, Mitsuyasu, Matsumoto, Hiroaki, Hanaki, Shunsuke, Masaki, Takahiro, Sato, Yuki, Matsuyama, Hideyasu, Kunieda, Kazuki, Nakagawa, Hidehiko, Shimada, Midori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847985/
https://www.ncbi.nlm.nih.gov/pubmed/34057812
http://dx.doi.org/10.1002/1878-0261.13030