The signal transducer CD24 suppresses the germ cell program and promotes an ectodermal rather than mesodermal cell fate in embryonal carcinomas

Testicular germ cell tumors (GCTs) are stratified into seminomas and nonseminomas. Seminomas share many histological and molecular features with primordial germ cells, whereas the nonseminoma stem cell population—embryonal carcinoma (EC)—is pluripotent and thus able to differentiate into cells of al...

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Detalles Bibliográficos
Autores principales: Skowron, Margaretha A., Becker, Teresa K., Kurz, Lukas, Jostes, Sina, Bremmer, Felix, Fronhoffs, Florian, Funke, Kai, Wakileh, Gamal A., Müller, Melanie R., Burmeister, Aaron, Lenz, Thomas, Stefanski, Anja, Stühler, Kai, Petzsch, Patrick, Köhrer, Karl, Altevogt, Peter, Albers, Peter, Kristiansen, Glen, Schorle, Hubert, Nettersheim, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847992/
https://www.ncbi.nlm.nih.gov/pubmed/34293822
http://dx.doi.org/10.1002/1878-0261.13066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8847992/
https://www.ncbi.nlm.nih.gov/pubmed/34293822
http://dx.doi.org/10.1002/1878-0261.13066

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