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Effect of imputation on gene network reconstruction from single-cell RNA-seq data
Despite the advances in single-cell transcriptomics, the reconstruction of gene regulatory networks remains challenging. Both the large amount of zero counts in experimental data and the lack of a consensus preprocessing pipeline for single-cell RNA sequencing (scRNA-seq) data make it hard to infer...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848013/ https://www.ncbi.nlm.nih.gov/pubmed/35199064 http://dx.doi.org/10.1016/j.patter.2021.100414 |