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Effect of Ultraviolet B Irradiation on Melanin Content Accompanied by the Activation of p62/GATA4-Mediated Premature Senescence in HaCaT Cells

OBJECTIVE: To explore the effect and mechanism of ultraviolet B (UVB) on melanin synthesis and premature senescence in human immortalized keratinocytes (HaCaT) cells. METHODS: HaCaT cells were irradiated with 0, 20, 50, 80, 100, 150, and 200 mJ/cm(2) of UVB. NaOH method was used for melanin content...

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Detalles Bibliográficos
Autores principales: Yan, Juan, Ma, Li-Ping, Liu, Fang, Sun, Bo, Tian, Mei, Lu, Xue, Liu, Hai-Xiang, Gao, Ling, Liu, Qing-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848062/
https://www.ncbi.nlm.nih.gov/pubmed/35185418
http://dx.doi.org/10.1177/15593258221075321