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Effect of Ultraviolet B Irradiation on Melanin Content Accompanied by the Activation of p62/GATA4-Mediated Premature Senescence in HaCaT Cells
OBJECTIVE: To explore the effect and mechanism of ultraviolet B (UVB) on melanin synthesis and premature senescence in human immortalized keratinocytes (HaCaT) cells. METHODS: HaCaT cells were irradiated with 0, 20, 50, 80, 100, 150, and 200 mJ/cm(2) of UVB. NaOH method was used for melanin content...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848062/ https://www.ncbi.nlm.nih.gov/pubmed/35185418 http://dx.doi.org/10.1177/15593258221075321 |