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Progesterone Inhibits the Establishment of Activation-Associated Chromatin During T(H)1 Differentiation

T(H)1-mediated diseases such as multiple sclerosis (MS) and rheumatoid arthritis (RA) improve during pregnancy, coinciding with increasing levels of the pregnancy hormone progesterone (P4), highlighting P4 as a potential mediator of this immunomodulation. Here, we performed detailed characterization...

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Detalles Bibliográficos
Autores principales: Rundquist, Olof, Nestor, Colm E., Jenmalm, Maria C., Hellberg, Sandra, Gustafsson, Mika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848251/
https://www.ncbi.nlm.nih.gov/pubmed/35185927
http://dx.doi.org/10.3389/fimmu.2022.835625