Cargando…

Progesterone Inhibits the Establishment of Activation-Associated Chromatin During T(H)1 Differentiation

T(H)1-mediated diseases such as multiple sclerosis (MS) and rheumatoid arthritis (RA) improve during pregnancy, coinciding with increasing levels of the pregnancy hormone progesterone (P4), highlighting P4 as a potential mediator of this immunomodulation. Here, we performed detailed characterization...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rundquist, Olof, Nestor, Colm E., Jenmalm, Maria C., Hellberg, Sandra, Gustafsson, Mika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848251/ https://www.ncbi.nlm.nih.gov/pubmed/35185927 http://dx.doi.org/10.3389/fimmu.2022.835625

Ejemplares similares

Progesterone Dampens Immune Responses in In Vitro Activated CD4(+) T Cells and Affects Genes Associated With Autoimmune Diseases That Improve During Pregnancy
por: Hellberg, Sandra, et al.
Publicado: (2021)

RNA-sequencing and mass-spectrometry proteomic time-series analysis of T-cell differentiation identified multiple splice variants models that predicted validated protein biomarkers in inflammatory diseases
por: Magnusson, Rasmus, et al.
Publicado: (2022)

Plasma protein profiling reveals dynamic immunomodulatory changes in multiple sclerosis patients during pregnancy
por: Papapavlou Lingehed, Georgia, et al.
Publicado: (2022)

TET2 as a tumor suppressor and therapeutic target in T-cell acute lymphoblastic leukemia
por: Bensberg, Maike, et al.
Publicado: (2021)

Multi-omics protein-coding units as massively parallel Bayesian networks: Empirical validation of causality structure
por: Zenere, Alberto, et al.
Publicado: (2022)

Using high-throughput multi-omics data to investigate structural balance in elementary gene regulatory network motifs
por: Zenere, Alberto, et al.
Publicado: (2021)

CD4(+) T-cell DNA methylation changes during pregnancy significantly correlate with disease-associated methylation changes in autoimmune diseases
por: Badam, Tejaswi V., et al.
Publicado: (2021)

Progesterone Modulation of Pregnancy-Related Immune Responses
por: Shah, Nishel M., et al.
Publicado: (2018)

Tissue-specific progesterone receptor-chromatin binding and the regulation of progesterone-dependent gene expression
por: Dinh, D. T., et al.
Publicado: (2019)

Prominent epigenetic and transcriptomic changes in CD4(+) and CD8(+) T cells during and after pregnancy in women with multiple sclerosis and controls
por: Zenere, Alberto, et al.
Publicado: (2023)

BET Protein Inhibition Regulates Macrophage Chromatin Accessibility and Microbiota-Dependent Colitis
por: Hoffner O’Connor, Michelle, et al.
Publicado: (2022)

Proteomics reveal biomarkers for diagnosis, disease activity and long-term disability outcomes in multiple sclerosis
por: Åkesson, Julia, et al.
Publicado: (2023)

Commentary: Drosophila GATA Factor Serpent Establishes Phagocytic Ability of Embryonic Macrophages
por: Valanne, Susanna, et al.
Publicado: (2018)

Role of female sex hormones, estradiol and progesterone, in mast cell behavior
por: Zierau, Oliver, et al.
Publicado: (2012)

Progesterone Aggravates Lung Fibrosis in a Mouse Model of Systemic Sclerosis
por: Vafashoar, Fatemeh, et al.
Publicado: (2021)

Mucosa associated invariant T and natural killer cells in active and budesonide treated collagenous colitis patients
por: Daferera, Niki, et al.
Publicado: (2022)

Whole course of treatment of autoimmune progesterone dermatitis that had spontaneously resolved during pregnancy: A case report and review of the literature
por: Huang, Yepei, et al.
Publicado: (2022)

The Chromatin Remodeler CHD8 Is Required for Activation of Progesterone Receptor-Dependent Enhancers
por: Ceballos-Chávez, María, et al.
Publicado: (2015)

Chromatin Remodeling Protein SMAR1 Is a Critical Regulator of T Helper Cell Differentiation and Inflammatory Diseases
por: Mirlekar, Bhalchandra, et al.
Publicado: (2017)

Histone H1 interphase phosphorylation becomes largely established in G(1 )or early S phase and differs in G(1 )between T-lymphoblastoid cells and normal T cells
por: Gréen, Anna, et al.
Publicado: (2011)

Altered Immune Response and Implantation Failure in Progesterone-Induced Blocking Factor-Deficient Mice
por: Csabai, Timea, et al.
Publicado: (2020)

High-progesterone environment preserves T cell competency by evading glucocorticoid effects on immune regulation
por: Kashiwagi, Hirofumi, et al.
Publicado: (2022)

DGK α and ζ Activities Control T(H)1 and T(H)17 Cell Differentiation
por: Yang, Jialong, et al.
Publicado: (2020)

Chromatin state dynamics during NK cell activation
por: Li, Yang, et al.
Publicado: (2017)

Identification of Profound Metabolic Alterations in Human Dendritic Cells by Progesterone Through Integrated Bioinformatics Analysis
por: Zhang, Sainan, et al.
Publicado: (2021)

Cohesin-Mediated Chromatin Interactions and Autoimmunity
por: Chandrasekaran, Venkataragavan, et al.
Publicado: (2022)

Transcriptomic Remodelling of Fetal Endothelial Cells During Establishment of Inflammatory Memory
por: Weiss, Elisa, et al.
Publicado: (2021)

Multimodal Regulation of NET Formation in Pregnancy: Progesterone Antagonizes the Pro-NETotic Effect of Estrogen and G-CSF
por: Giaglis, Stavros, et al.
Publicado: (2016)

Chromatin organization changes during the establishment and maintenance of the postmitotic state
por: Ma, Yiqin, et al.
Publicado: (2017)

Telomere chromatin establishment and its maintenance during mammalian development
por: Tardat, Mathieu, et al.
Publicado: (2017)

Inherited DNA methylation primes the establishment of accessible chromatin during genome activation
por: Liu, Guifen, et al.
Publicado: (2018)

Integrative Transcriptomics Reveals Activation of Innate Immune Responses and Inhibition of Inflammation During Oral Immunotherapy for Egg Allergy in Children
por: Karisola, Piia, et al.
Publicado: (2021)

The early function of cortisol in liver during Aeromonas hydrophila infection: Dynamics of the transcriptome and accessible chromatin landscapes
por: Jiang, Hucheng, et al.
Publicado: (2022)

Chromatin and Transcriptional Tango on the Immune Dance Floor
por: Roy, Ananda L., et al.
Publicado: (2014)

Chromatin Accessibility and Interactions in the Transcriptional Regulation of T Cells
por: Li, Peng, et al.
Publicado: (2018)

Sialylated Cervical Mucins Inhibit the Activation of Neutrophils to Form Neutrophil Extracellular Traps in Bovine in vitro Model
por: Bornhöfft, Kim F., et al.
Publicado: (2019)

Extracellular Chromatin Triggers Release of Soluble CEACAM8 Upon Activation of Neutrophils
por: Ribon, Matthieu, et al.
Publicado: (2019)

Adaptive and Innate Immune Responsiveness to Borrelia burgdorferi sensu lato in Exposed Asymptomatic Children and Children with Previous Clinical Lyme Borreliosis
por: Skogman, Barbro H., et al.
Publicado: (2012)

The Chromatin Signature of Pluripotency: Establishment and Maintenance
por: Di Giammartino, Dafne Campigli, et al.
Publicado: (2016)

Establishment and function of chromatin modification at enhancers
por: Tafessu, Amanuel, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_3jd92puf3hr3et0g5b5o93lqgn