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DENTIST—using long reads for closing assembly gaps at high accuracy

BACKGROUND: Long sequencing reads allow increasing contiguity and completeness of fragmented, short-read–based genome assemblies by closing assembly gaps, ideally at high accuracy. While several gap-closing methods have been developed, these methods often close an assembly gap with sequence that doe...

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Detalles Bibliográficos
Autores principales: Ludwig, Arne, Pippel, Martin, Myers, Gene, Hiller, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848313/
https://www.ncbi.nlm.nih.gov/pubmed/35077539
http://dx.doi.org/10.1093/gigascience/giab100