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Interpretable network-guided epistasis detection

BACKGROUND: Detecting epistatic interactions at the gene level is essential to understanding the biological mechanisms of complex diseases. Unfortunately, genome-wide interaction association studies involve many statistical challenges that make such detection hard. We propose a multi-step protocol f...

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Detalles Bibliográficos
Autores principales: Duroux, Diane, Climente-González, Héctor, Azencott, Chloé-Agathe, Van Steen, Kristel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848319/
https://www.ncbi.nlm.nih.gov/pubmed/35134928
http://dx.doi.org/10.1093/gigascience/giab093