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Interpretable network-guided epistasis detection
BACKGROUND: Detecting epistatic interactions at the gene level is essential to understanding the biological mechanisms of complex diseases. Unfortunately, genome-wide interaction association studies involve many statistical challenges that make such detection hard. We propose a multi-step protocol f...
Autores principales: | Duroux, Diane, Climente-González, Héctor, Azencott, Chloé-Agathe, Van Steen, Kristel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848319/ https://www.ncbi.nlm.nih.gov/pubmed/35134928 http://dx.doi.org/10.1093/gigascience/giab093 |
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