Development and validation of an UHPLC-Orbitrap-HRMS method for rapid determination of endogenous L-carnitine in patients on hemodialysis/peritoneal dialysis and its application to promote rational drug use

BACKGROUND: L-carnitine is an endogenous vitamin-like amino acid derivate which plays an essential role in energy metabolism and can be easily lost via dialysis. Deficiency of L-carnitine has great effects on many aspects of bodily functions. To determine the deficiency degree and adjust the supplem...

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Detalles Bibliográficos
Autores principales: Jiang, Wen-Ting, Tang, Liu-Xing, Pan, Jie, Su, Cun-Jin, Shen, Zhu, Hu, Zhan-Hong, Zhan, Zhou-Bing, Shi, Ai-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848361/
https://www.ncbi.nlm.nih.gov/pubmed/35282068
http://dx.doi.org/10.21037/atm-21-6784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848361/
https://www.ncbi.nlm.nih.gov/pubmed/35282068
http://dx.doi.org/10.21037/atm-21-6784

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