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Histone deacetylase inhibitor attenuates intestinal mucosal injury in fatally scalded rats

BACKGROUND: Severe burns, trauma and shock can cause intestinal epithelial barrier dysfunction, which can lead to intestinal endotoxemia and even sepsis and multi-organ dysfunction. Many studies have shown that histone deacetylase inhibitors (HDACIs) can improve cell tolerance to hypoxia and inflamm...

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Detalles Bibliográficos
Autores principales: Liu, Rui, Wang, Shu-Ming, Guo, Si-Jia, Ma, Ming-Ming, Fu, Yi-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8848362/
https://www.ncbi.nlm.nih.gov/pubmed/35282042
http://dx.doi.org/10.21037/atm-21-5766